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Thiethylperazine dimaleate
CAS No. 1179-69-7
Thiethylperazine dimaleate ( Toresten | Norzine | Thiethylperazine maleate )
产品货号. M26844 CAS No. 1179-69-7
Thiethylperazine dimaleate 是 D2 受体和 H1 受体的拮抗剂。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥648 | 有现货 |
|
| 10MG | ￥988 | 有现货 |
|
| 25MG | ￥1798 | 有现货 |
|
| 50MG | ￥3013 | 有现货 |
|
| 100MG | ￥4633 | 有现货 |
|
| 500MG | ￥9639 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Thiethylperazine dimaleate
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Thiethylperazine dimaleate 是 D2 受体和 H1 受体的拮抗剂。
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产品描述Thiethylperazine dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.(In Vitro):Thiethylperazine dimaleate dimaleate is an antagonist of the D2 receptor and H1 receptor. Thiethylperazine dimaleate dimaleate is an activator of ABCC1 and possesses antimicrobial, anti-emetic, and antipsychotic effects.(In Vivo):In APP/PS1 mice, Thiethylperazine dimaleate (3 mg/kg; intramuscular injection) causes a significant reduction of Aβ42 levels.
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体外实验Thiethylperazine could enhance the antibiotic (Vancomycin) activity at a concentration as low as 2 μg/mL. Thiethylperazine inhibits Vancomycin-sensitive E. faecalis ATCC 29212, Vancomycin-resistant E. faecalis ATCC 51299 and vancomycin-resistant E. faecalis (VREF) isolates with MIC values of 8 μg/mL, 16 μg/mL and 8 μg/mL, respectively.
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体内实验Thiethylperazine (3 mg/kg; intramuscular injection; twice daily; for 30 days; young APP/PS1 mice) treatment significantly reduces Aβ42 levels in APP/PS1 mice. Animal Model:Young Aβ precursor protein (APPswe) and mutant presenilin-1 (PS1) (APP/PS1) mice Dosage:3 mg/kg Administration:Intramuscular injection; twice daily; for 30 days Result:Significantly reduced Aβ42 levels in APP/PS1 mice.
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同义词Toresten | Norzine | Thiethylperazine maleate
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通路GPCR/G Protein
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靶点Dopamine Receptor
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number1179-69-7
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分子量631.76
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分子式C30H37N3O8S2
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 125 mg/mL (197.86 mM)
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SMILESOC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.CCSc1ccc2Sc3ccccc3N(CCCN3CCN(C)CC3)c2c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Otsuka M, et al. Reduction of bleomycin induced lung fibrosis by candesartan cilexetil, an angiotensin II type 1 receptor antagonist. Thorax. 2004 Jan;59(1):31-8.
